Hydroxyurea (500mg)
Durea 500 mg Capsule is used in the treatment of head and neck cancer and sickle cell anemia.
10 capsules in 1 strip
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Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Durea 500 mg Capsule may be taken with or without food, but it is better to take it at a fixed time.
In cancer, Durea 500 mg Capsule works by blocking an enzyme (ribonucleotide reductase) which is required for synthesis of DNA. This prevents the cancer cells from growing and multiplying. In sickle cell disease, it works by increasing fetal haemoglobin (HbF) levels in red blood cells (RBCs). This helps the RBCs assume a normal shape, improves blood flow and protects against complications such as painful sickle cell episodes.
Related Warnings
Interaction with alcohol is unknown. Please consult your doctor.
Durea 500 mg Capsule is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Durea 500 mg Capsule is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
Durea 500 mg Capsule may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.
Durea 500 mg Capsule should be used with caution in patients with kidney disease. Dose adjustment of Durea 500 mg Capsule may be needed. Please consult your doctor.
Regular monitoring of kidney function test and some blood tests may be advised while you are taking this medicine.
Durea 500 mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Durea 500 mg Capsule may be needed. Please consult your doctor.
