Insulin Lispro (25%)+ Insulin Lispro Protamine (75%)
Humalog Mix 25 Kwikpen 100IU/ml is normally prescribed along with a long-acting type of insulin or other diabetes medicines. Your doctor or nurse will teach you the correct way of injecting it under the skin. It should be taken 15 minutes before a meal or within 20 minutes after starting a meal. Don’t stop taking it unless your doctor tells you to.It is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Check your blood sugar levels regularly, keep track of your results and share them with your doctor. This is very important to work out the correct dose of the medicine for you.The most common side effect of this medicine is low blood sugar levels (hypoglycemia). To prevent this, it's important to always inject the correct dose of medicine only, have regular meals, and monitor your blood sugar levels regularly. Drinking excessive alcohol can also lead to a fall in your blood sugar levels. Other side effects include allergy at the injection site like redness, swelling, or hard lumps (lipodystrophy). Some people may also notice itching and rash while taking it.Do not use this medicine when you have low blood sugar levels (hypoglycemia). Tell your doctor if you have ever had kidney, liver or heart problems before starting treatment. Pregnant or breastfeeding women should also consult their doctor as the dose may need to be changed.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of Humalog Mix
3 ml Suspension for Injection
Image shown is a representation and may slightly vary from the actual product. Every effort is made to maintain accuracy of all information displayed.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Humalog Mix 25 Kwikpen 100IU/ml is a combination of two insulin preparations:.
Related Warnings
It is unsafe to consume alcohol with Humalog Mix 25 Kwikpen 100IU/ml.
Humalog Mix 25 Kwikpen 100IU/ml is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Humalog Mix 25 Kwikpen 100IU/ml should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Humalog Mix 25 Kwikpen 100IU/ml should be used with caution in patients with kidney disease. Dose adjustment of Humalog Mix 25 Kwikpen 100IU/ml may be needed. Please consult your doctor.
Regular monitoring of blood glucose levels is recommended for dose adjustment.
Humalog Mix 25 Kwikpen 100IU/ml should be used with caution in patients with liver disease. Dose adjustment of Humalog Mix 25 Kwikpen 100IU/ml may be needed. Please consult your doctor.
Regular monitoring of glucose levels is recommended for dose adjustment.
Wash your hands before injecting. Choose a site for injection. Clean the skin as instructed. Remove outer needle cap. Stabilize the skin by spreading it or pinching up a large area. Insert the needle as instructed. Press the knob. Pull the needle out and apply gentle pressure over the injection site for several seconds. Do not rub the area. Using the outer needle cap, unscrew the needle and dispose of it safely. Use of injection sites should be rotated so that the same site is not used more than approximately once a month.
The insulin device should be rotated in the palms of the hands ten times and inverted 180° ten times immediately before use to resuspend the insulin until it appears uniformly cloudy or milky. If not, repeat the above procedure until contents are mixed. Do not shake vigorously as this may cause frothing which may interfere with the correct measurement of the dose. The device/cartridge should be examined frequently and not be used if clumps of material are present or if solid white particles stick to the bottom or wall of the cartridge, giving a frosted appearance.
Yes, you need to prime your pen. If you do not prime, you may get too much or too little insulin. For priming, turn the dose knob to 2 units. Hold your pen with the needle pointing up. Tap the cartridge holder gently to collect air bubbles at the top. Continue holding your pen with the needle pointing up. Push the dose knob in until it stops and "0" is seen in the dose window. Hold the dose knob in and count to 5 slowly. You should see insulin at the tip of the needle.
Pushing the dose knob of the pen more slowly will make it easier to inject. Your needle may be blocked. Put on a new needle and prime the pen.
Low blood sugar (hypoglycemia) is the most common side effect. This may be associated with listlessness, confusion, palpitations, headache, sweating, and vomiting. Always carry a quick source of sugar such as glucose tablets, hard candy or juice to treat low blood sugar. Use of insulin is contraindicated during the episodes of hypoglycemia. Other possible side effects include severe life-threatening allergic reactions and reactions at the injection site.
If you are experiencing any side effects, please contact your doctor.
Insulin requirements may be increased by medications with hyperglycemic activity (medicines that increase glucose levels) such as corticosteroids, isoniazid, certain lipid-lowering drugs (e.g., niacin), estrogens, oral contraceptives, phenothiazines, and thyroid replacement therapy.
Insulin requirements may be decreased in the presence of drugs that increase insulin sensitivity or have hypoglycemic (glucose lowering) activity, such as oral antidiabetic agents, salicylates, sulfa antibiotics, certain antidepressants (monoamine oxidase inhibitors), angiotensin-converting-enzyme inhibitors, angiotensin II receptor blocking agents, beta-adrenergic blockers, inhibitors of pancreatic function (e.g., octreotide), and alcohol. Beta-adrenergic blockers may mask the symptoms of hypoglycemia in some patients.
Data on a large number of exposed pregnancies do not indicate any adverse effect of insulin lispro (main constituent of Humalog Mix 25 Kwikpen 100IU/ml) on pregnancy or on the health of the fetus/newborn. Insulin requirements usually fall during the first trimester and increase during the second and third trimesters. Patients with diabetes should inform their doctor, if they are pregnant or are contemplating the pregnancy. Careful monitoring of glucose control, as well as general health, is essential in pregnant patients with diabetes. Patients with diabetes who are breastfeeding may require adjustments in insulin dose, diet or both.
