Methotrexate (2.5mg)
Leetrexate 2.5mg Tablet may be used alone or in combination with other medicines. You should take it exactly as your doctor has advised. Taking too much of it can cause serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid consumption of alcohol while taking this medicine as it may increase your risk of liver damage.The most common side effects of this medicine are ulcerative stomatitis, hairloss, low blood cell count, increased liver enzymes, nausea, and abdominal distress. Your doctor may advise you to take folic acid to reduce some of these. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. This medicine may lower your ability to fight infections and lead to problems with your blood, liver, or kidneys. Your doctor may perform several tests such as blood tests, X-rays, and physical examinations both before and during treatment with this medicine to check for these.Before taking it, tell your doctor if you have problems related to the stomach, liver, or kidney, or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding as it may harm the baby.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of Leetrexate
10 tablets
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Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Leetrexate 2.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Leetrexate 2.5mg Tablet inhibits enzymes (dihydrofolate reductase), prevents cell division and leads to anti-inflammatory actions. Leetrexate 2.5mg Tablet kills cancer cells by preventing them from making DNA. Leetrexate 2.5mg Tablet can help control psoriasis by retarding the production of skin cells and suppressing inflammation. Leetrexate 2.5mg Tablet may treat rheumatoid arthritis by suppressing the immune system, preventing it from attacking the body's cells. This helps reduce the inflammation that causes swollen and stiff joints in rheumatoid arthritis, or damage to bowel in Crohn's disease.
Related Warnings
It is unsafe to consume alcohol with Leetrexate 2.5mg Tablet.
Leetrexate 2.5mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Leetrexate 2.5mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Leetrexate 2.5mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Leetrexate 2.5mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Leetrexate 2.5mg Tablet may be needed. Please consult your doctor.
Regular monitoring of kidney function test is advised while you are taking this medicine.
Leetrexate 2.5mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Leetrexate 2.5mg Tablet may be needed. Please consult your doctor.
Yes, Leetrexate 2.5mg Tablet can cause a sore mouth and mouth ulcers as side effects in some cases. Taking folic acid along with this medicine may help in reducing the ulcers. Ask your doctor if the dose can be reduced as dose reduction may further help in reducing the ulcers.
Folic acid is required to make new cells in the body and Leetrexate 2.5mg Tablet decreases the folic acid levels in the body. Folic acid can help reduce some of the common side effects of Leetrexate 2.5mg Tablet such as mouth ulcers, hair loss, nausea, heartburn, abdominal pain, fatigue, anemia and liver problems.
Regular blood tests will help your doctor to check your response to Leetrexate 2.5mg Tablet and monitor you for side effects. You will need to regularly check your liver function and your blood counts (white blood cells, red blood cells and platelets). Your doctor may also order additional tests depending on the results.
Leetrexate 2.5mg Tablet may decrease the activity of your immune system. As a result, you may develop serious infections. There have been rare reports which suggest occurrence of serious lung infections with Leetrexate 2.5mg Tablet use. If you have an active infection, Leetrexate 2.5mg Tablet should be used with extreme caution.
Yes, Leetrexate 2.5mg Tablet may affect fertility in both males and females. It may cause a decrease in sperm count in males and menstrual disturbances in females. No need to worry, these effects are reversible and disappear once the therapy is discontinued.
You should avoid pregnancy if your husband is taking Leetrexate 2.5mg Tablet. Also, it is advised that pregnancy should be further avoided for a minimum of 3 months after the therapy as it can lead to serious fetal abnormalities.
