Methotrexate (50mg)
Biotrexate 50mg Injection is given under the supervision of a healthcare professional and should not be self-administered. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid drinking alcohol as it may increase your risk of liver damage.The most common side effects of this medicine include nausea, vomiting, loss of appetite, abdominal pain, tiredness, mouth sores, and decreased white blood cells. Your doctor may advise you to take folic acid to reduce some of these. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is a very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver, or kidneys. Your doctor will advise you regular blood tests to check for these.Before taking it, tell your doctor if have stomach, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. You and your partner should avoid becoming pregnant or fathering a child for several months after your treatment with it has stopped. Your doctor may perform several tests such as blood tests, X-rays, and physical examinations both before and during treatment with this medicine.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of Biotrexate
2 ml Injection
Biochem Pharmaceutical Industries
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Your doctor or nurse will give you this medicine. Kindly do not self administer.
Biotrexate 50mg Injection is an anti-cancer medication. It works by blocking an enzyme (dihydrofolate reductase) involved in DNA synthesis in cancer cells. This slows the growth of cancer cells and eventually kills them.
Related Warnings
Caution is advised when consuming alcohol with Biotrexate 50mg Injection. Please consult your doctor.
Biotrexate 50mg Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Biotrexate 50mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Biotrexate 50mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Biotrexate 50mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Biotrexate 50mg Injection may be needed. Please consult your doctor.
Regular monitoring of kidney function test is advised while you are taking this medicine.
Biotrexate 50mg Injection should be used with caution in patients with liver disease. Dose adjustment of Biotrexate 50mg Injection may be needed. Please consult your doctor.
Use of Biotrexate 50mg Injection is not recommended in patients with severe liver disease.
Yes, Biotrexate 50mg Injection can cause a sore mouth and mouth ulcers as side effects in some cases. Taking folic acid along with this medicine may help in reducing the ulcers. Ask your doctor if the dose can be reduced as dose reduction may further help in reducing the ulcers.
Folic acid is required to make new cells in the body and Biotrexate 50mg Injection decreases the folic acid levels in the body. Folic acid can help reduce some of the common side effects of Biotrexate 50mg Injection such as mouth ulcers, hair loss, nausea, heartburn, abdominal pain, fatigue, anemia and liver problems.
Regular blood tests will help your doctor to check your response to Biotrexate 50mg Injection and monitor you for side effects. You will need to regularly check your liver function and your blood counts (white blood cells, red blood cells and platelets). Your doctor may also order additional tests depending on the results.
Biotrexate 50mg Injection may decrease the activity of your immune system. As a result, you may develop serious infections. There have been rare reports which suggest occurrence of serious lung infections with Biotrexate 50mg Injection use. If you have an active infection, Biotrexate 50mg Injection should be used with extreme caution.
Yes, Biotrexate 50mg Injection may affect fertility in both males and females. It may cause a decrease in sperm count in males and menstrual disturbances in females. No need to worry, these effects are reversible and disappear once the therapy is discontinued.
You should avoid pregnancy if your husband is taking Biotrexate 50mg Injection. Also, it is advised that pregnancy should be further avoided for a minimum of 3 months after the therapy as it can lead to serious fetal abnormalities.
