Top Salts
Isoniazid+Rifampicin+Ethambutol+Pyrazinamide
How Isoniazid+Rifampicin+Ethambutol+Pyrazinamide works
This is a combination of four medicines: Isoniazid, rifampicin, ethambutol and pyrazinamide which treat tuberculosis. Isoniazid works by preventing the TB bacteria from forming their own protective covering, while rifampicin inactivates a bacterial enzyme (RNA-polymerase) which is required by TB bacteria to make essential proteins and to reproduce. Together, they kill the bacteria and eradicate the infection. Ethambutol and pyrazinamide, on the other hand work by slowing the growth of these bacteria.
Side Effects
Nausea, Vomiting, Rash, Fever, Dark colored urine, Sweating, Increased sputum production, Salivation, Teary eyes, Peripheral neuropathy (tingling and numbness of feet and hand), Increased liver enzymes, Jaundice, Increased uric acid level in blood, Visual impairment
Usage
Isoniazid+Rifampicin+Ethambutol+Pyrazinamide is used in the treatment of tuberculosis.
