Top Salts
Probenecid
How Probenecid works
Probenecid decreases the uric acid levels in the blood by increasing its excretion in urine.
Side Effects
Hypersensitivity reaction, Gastrointestinal irritation
Usage
Probenecid is used in the treatment of gout.
Frequently Asked Questions
Q. Is probenecid an NSAID/ antibiotic/ sulfa drug/ diuretic?No. Probenecid belongs to a class of medications called uricosuric agents and is used to reduce high levels of uric acid in the body and to prevent and treat gout and gouty arthritis. It has no anti-inflammatory effect like NSAIDs or activity against infections like antibiotics or sulfa drugs. It is only used in combination with antibiotics (e.g. penicillin, ampicillin, amoxicillin etc.) to prolong their effect during infection. It has no effect on increasing urine output and is not a diuretic
Q. Probenecid is combined with penicillin/ why is probenecid given with penicillin/ how does probenecid work with penicillin/ how does probenecid increase penicillin/ what effect does probenecid have on penicillin?In certain cases of serious infections (e.g. gonorrhea or neurosyphillis) probenecid may be prescribed along with antibiotics like penicillin to prolong the effect of the antibiotics given by any route. Probenecid inhibits the elimination (excretion from blood into the urine) of certain antibiotics like penicillin by the kidneys thereby delaying its excretion and increasing concentration in the blood
Q. What is Probenecid used for?Probenecid is a uricosuric agent and is used to reduce high levels of uric acid in the body and to prevent and treat gout and gouty arthritis (pain and inflammation of small joints due to deposition of uric acid in the joint). It is also used to prolong the effect of antibiotics (e.g. penicillin)
Q. Does Probenecid cause kidney stones?Yes. Kidney stones are among the known side effects of Probenecid treatment.
