This is a combination of three medicines: Rifampicin, isoniazid and ethambutol which treat tuberculosis. Rifampicin works by inactivating a bacterial enzyme (RNA-polymerase) which is required by TB bacteria to make essential proteins and to reproduce, while isoniazid prevents these bacteria from forming their own protective covering. Together, they kill the bacteria and eradicate the infection. Ethambutol, on the other hand works by slowing the growth of these bacteria.
Nausea, Vomiting, Rash, Fever, Dark colored urine, Sweating, Increased sputum production, Salivation, Teary eyes, Increased liver enzymes, Jaundice, Visual impairment, Increased uric acid level in blood, Gout, Peripheral neuropathy (tingling and numbness of feet and hand)
Rifampicin+Isoniazid+Ethambutol is used in the treatment of tuberculosis.