Insulin Isophane / NPH is an intermediate-acting insulin, starts working within 10-20 minutes after injection. It works similar to insulin produced by the body. Insulin facilitates reuptake of sugar in muscle and fat cells and also suppresses the production of sugar in the liver.
Hypoglycemia (low blood sugar level), Injection site allergic reaction
Insulin Isophane / NPH is used in the treatment of diabetes.
Insulin isophane is a recombinant human insulin analogue (genetically modified insulin that is grown in a laboratory and similar to human insulin). It is an intermediate acting insulin preparation. Insulin isophane acts by replacing the normal production of insulin and by helping transfer sugar from the blood into other body tissues where it is utilized to generate energy. It also stops the liver from producing more sugar. Intermediate acting insulin preparations start acting within an hour or 2 of injection, and reach a period of peak activity that lasts up to 7 hours, following which the action trails off; overall duration of action ranges from 18 to 24 hours.