Trabectedin belongs to class of drugs called alkylating agents. It works by sticking to the DNA in cells and damaging it. This stops the cancer cells growing and multiplying..
Headache, Fatigue, Vomiting, Weakness, Nausea, Increased liver enzymes, Reduced blood platelets, Increased creatine phosphokinase level in blood, Decreased white blood cell count (neutrophils), Decreased appetite, Constipation
Trabectedin is used in the treatment of soft tissue sarcoma.
Yes, Trabectedin is FDA approved.