This is a combination of two diuretics: Metolazone and spironolactone which reduce edema (swelling). They work by removing extra water and certain electrolytes from the body through urine. Over time, metolazone also relaxes blood vessels but causes potassium loss. Spironolactone is added as it conserves potassium, thereby balancing its levels in the body.
Diarrhoea, Stomach upset, Glucose intolerance, Breast enlargement in male, Irregular menstrual cycles, Increased blood lipid level, Increased uric acid level in blood, Electrolyte imbalance, Impotence
Metolazone+Spironolactone is used in the treatment of high blood pressure.