Top Salts
Vincristine
How Vincristine works
Vincristine blocks replication of genetic material (DNA) in the cancer cells. Thus it stops the growth and multiplication of cancer cells.
Side Effects
Hair loss, Peripheral neuropathy (tingling and numbness of feet and hand), Constipation
Usage
Vincristine is used in the treatment of breast cancer, non-small cell lung cancer, pancreatic cancer, kidney cancer, blood cancer, multiple myeloma, lymphomas and bone cancer.
Frequently Asked Questions
Q. Is Vincristine cardiotoxic/ototoxic?Vincristine when used in combination with other drugs has shown to be cardiotoxic/ototoxic with unknown cause
Q. Is Vincristine an alkylating agent/ an anthracycline?Vincristine is vinca alkaloid and not an alkylating agent/ an anthracycline
Q. Is Vincristine a vesicant?Vincristine is a vesicant (irritant) and can cause damage to the blood vessels if it is not administered properly
Q. Is Vincristine non DNA binding?Vincristine does not bind to DNA
Q. Is Vincristine neuropathy reversible?Vincristine neuropathy is not reversible
Q. Is Vincristine FDA approved?Vincristine is a FDA approved medication
Q. Is Vincristine FDA approved?Vincristine is a FDA approved medication
Q. Is Vincristine cytotoxic?Vincristine is a cytotoxic drug
Q. Does Vincristine cause hair loss/infertility/ lower blood counts/ neutropenia/ neuropathy/ fever/ nausea?These side effects are commonly observed with the use of Vincristine drug
Q. How does Vincristine affect mitosis?Vincristine works by interfering with the growth of cancer cells (mitotic inhibition) and slows their spread in the body by causing an arrest of cell division in metaphase
Q. Where does Vincristine come from?Vincristine is a plant alkaloid comes from the source called Vinca rosea Linn.
