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Isoniazid+Vitamin B6 (Pyridoxine)+Rifampicin
How Isoniazid+Vitamin B6 (Pyridoxine)+Rifampicin works
This is a combination of three medicines: Isoniazid, vitamin B6 (pyridoxine) and rifampicin. Isoniazid prevents the TB bacteria from forming their own protective covering, while rifampicin works by inactivating a bacterial enzyme (RNA-polymerase) which is required by these bacteria to make essential proteins and to reproduce. Together, they kill the bacteria and eradicate the infection. Vitamin B6 (pyridoxine) is added to prevent nerve damage which may be a side effect of isoniazid.
Side Effects
Nausea, Vomiting, Rash, Fever, Dark colored urine, Sweating, Increased sputum production, Salivation, Teary eyes, Peripheral neuropathy (tingling and numbness of feet and hand), Increased liver enzymes, Jaundice
Usage
Isoniazid+Vitamin B6 (Pyridoxine)+Rifampicin is used in the treatment of tuberculosis.
