Top Salts
Sirolimus
How Sirolimus works
Sirolimus suppresses the activity of body's immune system and prevents rejection of the transplanted organ.
Side Effects
Nausea, Headache, Abdominal pain, Viral infection, Pneumonia, Reduced blood platelets, Increased heart rate, Decreased white blood cell count, Anemia, Urinary tract infection, Diarrhoea, Increased blood pressure, Bacterial infection, Fungal infection, Constipation, Herpes virus infection
Usage
Sirolimus is used in transplant rejection of kidney.
Frequently Asked Questions
Q. Is Sirolimus dialyzable?Sirolimus is not dialyzable to significant extent. i.e. it will not be eliminated after dialysis.
Q. Is Sirolimus a calcineurin inhibitor?Sirolimus is not a calcineurin inhibitor, but it has a similar suppressive effect on the immune system
Q. Is Sirolimus cytotoxic?Sirolimus is a cytotoxic agent
Q. What is Sirolimus-eluting stent?The Sirolimus-eluting stent is a metal stent coated with 140 µg/cm2 of Sirolimus blended with synthetic polymers. After stent implantation, Sirolimus is slowly released causing localized inhibition of growth of smooth muscle cells in the wall of the blood vessel in which it is implanted over a period of about 1 month
Q. Does Sirolimus cause hair loss?Sirolimus causes hair loss
Q. Why does Sirolimus cause hyperlipidemia?Sirolimus alters certain body pathways to increase lipid/fat synthesis by the liver, thereby causing hyperlipidemia.
