Isosorbide (20mg) + Hydralazine (37.5mg)
Apresol Plus Tablet is used in the treatment of heart failure.
1 Strip of 10 Tablet
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Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Apresol Plus Tablet may be taken with or without food, but it is better to take it at a fixed time.
Apresol Plus Tablet is a combination of two medicines: Isosorbide dinitrate and Hydralazine. Isosorbide dinitrate is a nitrate which relaxes the blood vessels and decreases the oxygen demand of the heart. Hydralazine is a potassium channel opener which acts as an antioxidant and lessens tolerance to isosorbide dinitrate, thereby preserving its capacity to relax blood vessels. Together, they improve symptoms of heart failure.
Related Warnings
Apresol Plus Tablet may cause symptoms such as flushing, increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol (Disulfiram reactions).
Apresol Plus Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Apresol Plus Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Do not drive unless you are feeling well.
As Apresol Plus Tablet may cause headaches or lead to difficulty in concentration and this may affect your ability to drive.
Apresol Plus Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Apresol Plus Tablet may be needed. Please consult your doctor.
Regular monitoring of blood pressure is recommended for better dose adjustment.
Apresol Plus Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Apresol Plus Tablet may not be needed in these patients. Please consult your doctor.
