Gabapentin (400mg) + Nortriptyline (10mg)
Pentanerv-NT 400mg/10mg Tablet is used in the treatment of neuropathic pain.
1 Strip of 10 Tablet
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Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pentanerv-NT 400mg/10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Pentanerv-NT 400mg/10mg Tablet is a combination of two medicines: Gabapentin and Nortriptyline. Gabapentin is an alpha 2 delta ligand which decreases the pain by modulating calcium channel activity of the nerve cells. Nortriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Together, they relieve neuropathic pain (pain from damaged nerves).
Related Warnings
Pentanerv-NT 400mg/10mg Tablet may cause excessive drowsiness and calmness with alcohol.
Pentanerv-NT 400mg/10mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Pentanerv-NT 400mg/10mg Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
Do not drive unless you are feeling well.
As Pentanerv-NT 400mg/10mg Tablet may affect your alertness which may affect your ability to drive.
Pentanerv-NT 400mg/10mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Pentanerv-NT 400mg/10mg Tablet may be needed. Please consult your doctor.
Pentanerv-NT 400mg/10mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Pentanerv-NT 400mg/10mg Tablet may be needed. Please consult your doctor.
Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine. Use of Pentanerv-NT 400mg/10mg Tablet is not recommended in patients with severe liver disease.
