Glibenclamide (5mg)+ Metformin (500mg)
Glybonil Plus 5mg/500mg Tablet should be taken with food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you and this may change from time to time according to how it is working according to your blood sugar levels.Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.The most common side effect of Glybonil Plus 5mg/500mg Tablet is low blood glucose levels (hypoglycemia). Make sure you recognize the signs of having low blood glucose levels, such as sweating, dizziness, headache, and shaking and know how to deal with it. To prevent this, it's important to have regular meals and always carry a fast-acting source of glucose such as sugary food or fruit juice with you. Drinking alcohol can also increase your risk of low blood sugar levels and should be avoided. Other side effects that may be seen on taking this medicine include taste changes, nausea, diarrhea, stomach pain, headache, and upper respiratory tract infection. Some people may find that they put on weight with this medicine.You should not take it if you have type 1 diabetes mellitus, if you have diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease. It may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of Glybonil Plus
10 tablets
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Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glybonil Plus 5mg/500mg Tablet is to be taken with food.
Glybonil Plus 5mg/500mg Tablet is a combination of two antidiabetic medicines: Glibenclamide and Metformin.
Related Warnings
It is unsafe to consume alcohol with Glybonil Plus 5mg/500mg Tablet.
Glybonil Plus 5mg/500mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Glybonil Plus 5mg/500mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
It is not known whether Glybonil Plus 5mg/500mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Glybonil Plus 5mg/500mg Tablet is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.
Glybonil Plus 5mg/500mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Glybonil Plus 5mg/500mg Tablet may be needed. Please consult your doctor.
Glybonil Plus 5mg/500mg Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.
Glybonil Plus 5mg/500mg Tablet is a combination of two medicines: Glibenclamide and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves the blood glucose levels in adults when taken along with proper diet and regular exercise. Glibenclamide lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of Type 1 DM.
Type 2 diabetes is the most common form of diabetes. It is a condition in which the body is unable to make enough insulin, and the insulin produced by the body does not work well. When this happens, the glucose level in the blood rises and leads to serious medical problems. Symptoms of high blood sugar include frequent urination, increased thirst and increased hunger. Diabetes, if not treated properly, can cause long-term complications like neuropathy (nerve damage), nephropathy (kidney damage), eye damage (retinopathy), foot problems and also a higher risk of developing heart diseases.
The use of Glybonil Plus 5mg/500mg Tablet is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use, it can also lead to vitamin B12 deficiency.
Yes, the use of Glybonil Plus 5mg/500mg Tablet can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with this medicine. So, regular monitoring of blood sugar level is important. Always keep a quick source of sugar like glucose tablets, honey or fruit juice with you.
Yes, the use of Glybonil Plus 5mg/500mg Tablet can cause vitamin B12 deficiency on long-term use as it interferes with the absorption of vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient may feel a tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of Vitamin B12 from outside sources at least once every year.
The use of Glybonil Plus 5mg/500mg Tablet should be avoided in patients with known allergy to any of the components or excipients of this medicine. It should also be avoided in patients with moderate to severe kidney disease and in patients with underlying metabolic acidosis including diabetic ketoacidosis.
No, it is not safe to take Glybonil Plus 5mg/500mg Tablet along with alcohol, as it may lower your low blood sugar levels (hypoglycemia) and can increase the chances of lactic acidosis.
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
