Glimepiride (1mg) + Metformin (500mg) + Pioglitazone (15mg)
Trigulin 1 Tablet ER is used in the treatment of type 2 diabetes.
1 Strip of 15 Tablet
Glenmark Pharmaceuticals Ltd
Image shown is a representation and may slightly vary from the actual product. Every effort is made to maintain accuracy of all information displayed.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Trigulin 1 Tablet ER is to be taken with food.
Trigulin 1 Tablet ER may cause stomach upset if taken empty stomach.
Trigulin 1 Tablet ER is a combination of three antidiabetic medicines: Glimepiride, Metformin and Pioglitazone. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide. It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body"s sensitivity to insulin. Pioglitazone is a thiazolidinedione which further increases insulin sensitivity.
Related Warnings
Taking pioglitazone with alcohol may affect blood glucose levels in patients with diabetes.
Trigulin 1 Tablet ER may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Trigulin 1 Tablet ER is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Monitor the breastfed babyâs blood sugar during treatment with Trigulin 1 Tablet ER
Your ability to drive may be affected if your blood sugar is low or high. If this happens, do not drive.
Trigulin 1 Tablet ER should be used with caution in patients with kidney disease. Dose adjustment of Trigulin 1 Tablet ER may be needed. Please consult your doctor.
Use of Trigulin 1 Tablet ER is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Trigulin 1 Tablet ER should be used with caution in patients with liver disease. Dose adjustment of Trigulin 1 Tablet ER may be needed. Please consult your doctor.
Use of Trigulin 1 Tablet ER is not recommended in patients with severe liver disease.