Propranolol (40mg)+ Flunarizine (10mg)
Grenate Plus 40mg/10mg Tablet should be taken on empty stomach, but try to have it same time regularly at a fixed time preferably at night. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you. Lifestyle modifications like avoiding stress, smoking, and processed food items may help this medicine work better.Few common side effects of this medicine include weight gain, slow heart rate, tiredness, depression, drowsiness and cold extremities. It may cause sleepiness so try not to drive or do anything that requires mental focus or rise slowly while from sitting position. The drug has the ability to hide the symptoms of the blood sugar level, hence monitor your blood sugar level regularly as well as blood pressure while taking this medicine.Before taking this medicine, let your doctor know if you have liver or kidney, or depression disease, or if you are pregnant or breastfeeding. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of Grenate Plus
10 tablets
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Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Grenate Plus 40mg/10mg Tablet is to be taken empty stomach.
Grenate Plus 40mg/10mg Tablet is a combination of two medicines: Propranolol and Flunarizine, which prevents migraine. Propranolol is a beta blocker and Flunarizine is a calcium channel blocker. They work by stabilizing the reactive nerve cells and increasing the threshold to migraine activation. They also inhibit cortical spreading depression (CSD- electric waves that move across the brain and cause pain and inflammation).
Related Warnings
It is unsafe to consume alcohol with Grenate Plus 40mg/10mg Tablet.
Grenate Plus 40mg/10mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Information regarding the use of Grenate Plus 40mg/10mg Tablet during breastfeeding is not available. Please consult your doctor.
Grenate Plus 40mg/10mg Tablet may cause side effects which could affect your ability to drive.
Grenate Plus 40mg/10mg Tablet may cause visual disturbances, hallucinations, fatigue, mental confusion, dizziness or tiredness. This may affect your driving ability.
Grenate Plus 40mg/10mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Grenate Plus 40mg/10mg Tablet may not be needed in these patients. Please consult your doctor.
Grenate Plus 40mg/10mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Grenate Plus 40mg/10mg Tablet may be needed. Please consult your doctor.
Regular monitoring of blood pressure is advisable for dose adjustment.
Use of Grenate Plus 40mg/10mg Tablet is considered to be harmful for patients with allergy to any of the ingredients or excipients of this medicine. This medicine contains propranolol, so its use should be avoided in patients with asthma, slow heart rate, abnormal heart rhythms, or heart conditions like AV block or sick sinus syndrome. Since this medicine also contains flunarizine, the use of this medicine should be avoided in patients with the history of depression or Parkinson's disease.
Keep Grenate Plus 40mg/10mg Tablet in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Grenate Plus 40mg/10mg Tablet is given as a prophylactic treatment for the prevention of migraine headaches. Do not stop taking this medicine until advised by your doctor as it may cause your migraine episodes to return. This medicine contains propranolol and a sudden withdrawal of propranolol may cause sweating, shaking, irregular or fast heartbeat, worsening of underlying angina or heart attack. You must take Grenate Plus 40mg/10mg Tablet exactly as advised by your doctor.
No, Grenate Plus 40mg/10mg Tablet does not help in relieving a migraine headache that has already started. It can only be used for preventing any new episode of migraine headaches.
