Levodopa (50mg) + Carbidopa (12.5mg) + Entacapone (200mg)
Syncapone 50 Tablet is used in the treatment of Parkinson"s disease.
1 Strip of 10 Tablet
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Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Syncapone 50 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Avoid Syncapone 50 Tablet with high protein meals such as cottage cheese, Swiss cheese, protein powder, eggs and milk.
Syncapone 50 Tablet is a combination of three medicines: Levodopa, Carbidopa and Entacapone which treat Parkinsonism. Levodopa is a Carbidopa precursor which gets converted to dopamine, a chemical messenger that controls movement in the brain. Carbidopa is a peripheral decarboxylase inhibitor which prevents the breakdown of Levodopa allowing it to enter the brain and increase dopamine levels. Entacapone is COMT inhibitor which causes higher and more sustained levels of levodopa in blood, leading to greater relief from the symptoms of Parkinsonâs disease.
Related Warnings
Syncapone 50 Tablet may cause excessive drowsiness and calmness with alcohol.
Syncapone 50 Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Syncapone 50 Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
Do not drive unless you are feeling well.
Caution is advised when driving or operating machinery.
Syncapone 50 Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Syncapone 50 Tablet may not be needed in these patients. Please consult your doctor.
Syncapone 50 Tablet should be used with caution in patients with liver disease. Dose adjustment of Syncapone 50 Tablet may be needed. Please consult your doctor.
