Paracetamol (500mg) + Domperidone (20mg)
Grenil Tablet is used in the treatment of migraine.
1 Strip of 10 Tablet
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Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Grenil Tablet is to be taken empty stomach.
Grenil Tablet is a combination of two medicines: Domperidone and Paracetamol/Acetaminophen. Domperidone is a prokinetic which works on the region in the brain that controls vomiting. It also increases the movement of the stomach and intestines, allowing food to move more easily through the stomach. This prevents nausea and vomiting caused due to migraine. Paracetamol/Acetaminophen is an analgesic (pain reliever) and an anti-pyretic (fever reducer) which blocks the release of certain chemical messengers that cause pain and fever associated with migraine.
Related Warnings
Taking Domperidone+Paracetamol/Acetaminophen with alcohol can cause liver damage.
Grenil Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Grenil Tablet is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
Grenil Tablet may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.
Grenil Tablet should be used with caution in patients with kidney disease. Dose adjustment of Grenil Tablet may be needed. Please consult your doctor.
Grenil Tablet should be used with caution in patients with liver disease. Dose adjustment of Grenil Tablet may be needed. Please consult your doctor.
However, the use of Grenil Tablet is not recommended in patients with severe liver disease and active liver disease.