Flunarizine (10mg) + Propranolol (40mg)
Provonol-F Capsule SR is used for preventive treatment of migraine.
10 capsule sr in 1 strip
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Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Provonol-F Capsule SR is to be taken empty stomach.
Provonol-F Capsule SR is a combination of two medicines: Propranolol and Flunarizine, which prevents migraine. Propranolol is a beta blocker and Flunarizine is a calcium channel blocker. They work by stabilizing the reactive nerve cells and increasing the threshold to migraine activation. They also inhibit cortical spreading depression (CSD- electric waves that move across the brain and cause pain and inflammation).
Related Warnings
Taking Propranolol with alcohol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate.
Provonol-F Capsule SR may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
No information is available on the use of Provonol-F Capsule SR during lactation. Please consult your doctor.
Do not drive unless you are feeling well.
Provonol-F Capsule SR may cause visual disturbances, hallucinations, fatigue, mental confusion, dizziness or tiredness. This may affect your driving ability.
Provonol-F Capsule SR is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Provonol-F Capsule SR may not be needed in these patients. Please consult your doctor.
Provonol-F Capsule SR should be used with caution in patients with liver disease. Dose adjustment of Provonol-F Capsule SR may be needed. Please consult your doctor.
Regular monitoring of blood pressure is advisable for dose adjustment.
